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The antimicrobial defense of Drosophila : a paradigm for innate immunity /...

Title: The antimicrobial defense of Drosophila : a paradigm for innate immunity / Jules Hoffmann.
Author(s)/Relationship(s): Hoffmann, J. (Jules), 1941-
Publisher: [Bethesda, Md. : National Institutes of Health, 2011]
Related Names: National Institutes of Health (U.S.)
Series: Wednesday afternoon lecture series
Description: 1 online resource (1 streaming video file (1 hr., 1 min.) : sd., col.).
Content Type: two-dimensional moving image
Media Type: computer
Carrier Type: online resource
Language: eng
Electronic Links:
MeSH Subjects: Immunity, Innate --immunology
Anti-Infective Agents --pharmacology
Drosophila --immunology
Models, Animal
Summary: (CIT): The last twenty years have experienced an unprecedented advance in our understanding of innate immunity in Metazoans and Plants. Up to the early nineties of the last century, little information had been obtained about pathogen recognition by the innate immune system and about the effector mechanisms induced by invading microorganisms. Drosophila, with its easily tractable genetics, can be credited with having made significant contributions to our present understanding of the basics of innate defenses. The presentation will review our current understanding, but will also address the many unresolved questions which await further in-depth analysis. A phylogenetic perspective will try to integrate the data obtained by studying Drosophila immunity, into the more general framework of invertebrate and vertebrate immune defenses.
Notes: Title from title screen.
NLM Unique ID: 101566820
Other ID Numbers: (DNLM)CIT:16749


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